Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080783 | 0.87 | POLB (0.48) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL6985405 | 0.86 | HSD17B10 (0.46) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL6980241 | 0.86 | POLB (0.48) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL6982704 | 0.83 | ITGB3 (0.44) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL6985632 | 0.81 | ITGB3 (0.41) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL6978012 | 0.81 | NR3C1 (0.49) | MAPTALDH1A1LMNAMEN1HPGD | |
| Hydrochloric Acid SCHEMBL6985575 | 0.81 | RXRA (0.48) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL6982241 | 0.80 | NR3C1 (0.48) | MAPTALDH1A1LMNAMEN1HPGD | |
| Hydrochloric Acid SCHEMBL7956681 | 0.80 | NR3C1 (0.42) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL7958817 | 0.80 | NR3C1 (0.47) | MAPTALDH1A1LMNAMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |