Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985013 | 0.86 | KMT2A (0.39) | ADRA1BADRA1AMCHR1ALDH1A1POLB | |
| SCHEMBL6987894 | 0.84 | ADRA1B (0.37) | ADRA1BALDH1A1POLBLMNAKMT2A | |
| SCHEMBL6987065 | 0.82 | POLB (0.39) | ADRA1BADRA1AALDH1A1POLBKMT2A | |
| SCHEMBL6985684 | 0.82 | ADRA1B (0.47) | ADRA1BADRA1A | |
| SCHEMBL6977033 | 0.81 | KMT2A (0.38) | RAB9AADRA1BADRA1AALDH1A1POLB | |
| SCHEMBL6981559 | 0.81 | ADRA1B (0.41) | ADRA1BPOLBKMT2ATDP1 | |
| SCHEMBL6986602 | 0.80 | KDM4E (0.41) | SMN1; SMN2ALDH1A1POLBLMNAKMT2A | |
| SCHEMBL4875098 | 0.80 | CYP2D6 (0.36) | SLC6A2SLC6A3RAB9AADRA1BADRA1A | |
| SCHEMBL6978015 | 0.80 | MEN1 (0.39) | RAB9AADRA1BADRA1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6979847 | 0.80 | ADRA1B (0.41) | ADRA1BALDH1A1POLBLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289965-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090081-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-29 | — | — | WO | disclosed |