SCHEMBL6985697

SCHEMBL6985697

C=CCOP(=O)(OCC=C)C(=O)c1c(OC)cccc1C(=O)Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.40
LIG1 P18858 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
KDM4E B2RXH2 3/20 0.35
POLB P06746 1/20 0.35
KMT2A Q03164 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CYP3A4 P08684 1/20 0.35
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
KCNK3 O14649 1/20 0.34
KCNK9 Q9NPC2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4683233 0.77 CTSD (0.39) CTSDLIG1KDM4EPOLBKMT2A
SCHEMBL6985699 0.76 CTSD (0.38) CTSDLIG1KDM4EPOLBKMT2A
SCHEMBL67966 0.71 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL4684488 0.68 SMN1; SMN2 (0.41) CTSDLIG1CA12CA1CA2
SCHEMBL11400410 0.67 CA12 (0.57) CTSDCA12CA1CA2CA7
SCHEMBL13811159 0.67 PPARA (0.48) CA12CA1CA2CA7CA9
SCHEMBL1428 0.67 LIG1 (0.67) LIG1CA12CA1CA9KDM4E
SCHEMBL4684955 0.67 CXCR5 (0.36) LIG1KDM4EPOLBKMT2ASMN1; SMN2
SCHEMBL104667 0.67 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL28233354 0.66 LIG1 (0.54) LIG1KDM4EKMT2ACYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1362856-A1 WATER-SOLUBLE TRIAZOLE FUNGICIDE Sankyo Company, Limited (JP) 2003-11-19 EP disclosed