SCHEMBL6985699

SCHEMBL6985699

C=CCOP(=O)(OCC=C)C(O)c1c(OC)cccc1C(=O)Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.38
LIG1 P18858 1/20 0.37
CNR2 P34972 2/20 0.35
TAS1R3 Q7RTX0 1/20 0.34
TAS1R1 Q7RTX1 1/20 0.34
KDM4E B2RXH2 5/20 0.34
POLB P06746 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MEN1 O00255 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP3A4 P08684 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ADRB2 P07550 1/20 0.34
ADRB1 P08588 1/20 0.34
ADRB3 P13945 1/20 0.34
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
ALOX12 P18054 1/20 0.33
MAPK10 P53779 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6985697 0.76 CTSD (0.40) CTSDLIG1CNR2KDM4EPOLB
SCHEMBL4683233 0.75 CTSD (0.39) CTSDLIG1CNR2KDM4EPOLB
SCHEMBL5428398 0.71 KDM4E (0.51) CTSDTAS1R3TAS1R1KDM4EHTT
SCHEMBL4684488 0.67 SMN1; SMN2 (0.41) CTSDLIG1KDM4EPOLBSMN1; SMN2
SCHEMBL6984167 0.67 GRM4 (0.30)
SCHEMBL1428 0.65 LIG1 (0.67) LIG1KDM4EMEN1KMT2ACYP3A4
SCHEMBL4684955 0.65 CXCR5 (0.36) LIG1KDM4EPOLBSMN1; SMN2MEN1
SCHEMBL28233354 0.65 LIG1 (0.54) LIG1KDM4EMEN1KMT2ACYP3A4
SCHEMBL431 0.64 CTSD (0.63) CTSDSMN1; SMN2HTTALDH1A1HPGD
SCHEMBL29392137 0.64 CTSD (0.63) CTSDSMN1; SMN2HTTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1362856-A1 WATER-SOLUBLE TRIAZOLE FUNGICIDE Sankyo Company, Limited (JP) 2003-11-19 EP disclosed