SCHEMBL104667

SCHEMBL104667

COc1cccc(OC)c1C(=O)Cl

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.65
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
CA7 P43166 2/20 0.65
CA9 Q16790 2/20 0.65
CA14 Q9ULX7 2/20 0.65
SMN1; SMN2 Q16637 1/20 0.49
ALDH1A1 P00352 2/20 0.48
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
LMNA P02545 1/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
ALOX12 P18054 1/20 0.46
MAPK1 P28482 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CA4 P22748 1/20 0.46
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6329502 0.90 CA1 (0.59) CA12CA1CA2CA7CA9
Toluene SCHEMBL28811560 0.89 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL1622269 0.88 ALDH1A1 (0.63) CA12CA1CA2CA7CA9
SCHEMBL1623297 0.88 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL11516673 0.87 SMN1; SMN2 (0.52) CA12CA1CA2CA7CA9
SCHEMBL1265737 0.86 CA12 (0.55) CA12CA1CA2CA7CA9
SCHEMBL16239034 0.86 CA12 (0.55) CA12CA1CA2CA7CA9
SCHEMBL17746094 0.85 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL9713000 0.84 CA12 (0.49) CA12CA1CA2CA7CA9
SCHEMBL1761063 0.82 CA12 (0.50) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 687 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113651850-A Co-production preparation of monoacylphosphines and bisacylphosphines and their oxides 深圳有为技术控股集团有限公司 2021-11-16 CN claimed
US-12605353-B2 PDIA4 inhibitors and use thereof for inhibiting β-cell pathogenesis and treating diabetes ACADEMIA SINICA (TW) 2026-04-21 US disclosed
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME KULEON LLC (US) 2026-04-02 US disclosed
EP-4069252-B1 PDIA4 INHIBITORS AND USE THEREOF FOR INHIBITING SS-CELL PATHOGENESIS AND TREATING DIABETES ACADEMIA SINICA (CN) 2025-12-10 EP disclosed
US-20250340513-A1 NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS KULEON LLC (US) 2025-11-06 US disclosed
US-12441683-B2 7-methyl indole analogs and dosage forms containing the same Kuleon, LLC (US) 2025-10-14 US disclosed
US-20250282722-A1 7-METHYL INDOLE ANALOGS AND DOSAGE FORMS CONTAINING THE SAME KULEON LLC (US) 2025-09-11 US disclosed
US-12344582-B2 Mixed serotonin 5-HT2A/2C receptor agonists and methods for treating pain and depression Kuleon, LLC (US) 2025-07-01 US disclosed
US-12275701-B2 Neuroplastogens and non-hallucinogenic serotonin 5-HT2A receptor modulators Kuleon, LLC (US) 2025-04-15 US disclosed
US-20250091991-A1 MIXED SEROTONIN 5-HT2A/2C RECEPTOR AGONISTS AND METHODS FOR TREATING PAIN AND DEPRESSION Kuleon, LLC (US) 2025-03-20 US disclosed
US-3998958-A Pyrrolidylidene, piperidylidene and hexahydroazepinylidene ureas as CNS depressants MCNEIL LABORATORIES, INCORPORATED (US) 1976-12-21 US disclosed
US-3997532-A Intermediates for producing semi-synthetic cephalosporins AMERICAN HOME PRODUCTS CORPORATION (US) 1976-12-14 US disclosed
US-3994911-A PHOSPHORYLATED AMERICAN HOME PRODUCTS CORPORATION (US) 1976-11-30 US disclosed
US-3985783-A Process for ring acylation of phenols THE DOW CHEMICAL COMPANY (US) 1976-10-12 US disclosed
US-3965093-A 6-Arylthio penicillanic acid and derivatives thereof E. R. SQUIBB & SONS, INC. (US) 1976-06-22 US disclosed
US-3962227-A ANTIBIOTICS ELI LILLY AND COMPANY (US) 1976-06-08 US disclosed
US-3962215-A PHOSPHORYLATION, ACYLATION, WATER, ACID CHLORIDE, ALCOHOL AMERICAN HOME PRODUCTS CORPORATION (US) 1976-06-08 US disclosed
US-3954744-A ANTIBACTERIAL E. R. SQUIBB & SONS, INC. (US) 1976-05-04 US disclosed
US-3935186-A Intermediates for producing semi-synthetic penicillins and cephalosporins and methods of production AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-27 US disclosed
US-3933810-A ANTIBACTERIAL AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME HTR2C, HTR7, HTR6 CA12 2458/4885CA1 1158/4885CA2 2151/4885
US-20250282722-A1 7-METHYL INDOLE ANALOGS AND DOSAGE FORMS CONTAINING THE SAME HTR7, HTR2C, HTR1A CA12 4829/4885CA1 4571/4885CA2 4598/4885
US-12441683-B2 7-methyl indole analogs and dosage forms containing the same HTR7, HTR2C, HTR1A CA12 4829/4885CA1 4571/4885CA2 4598/4885
US-12275701-B2 Neuroplastogens and non-hallucinogenic serotonin 5-HT2A receptor modulators HTR2A, HTR2C, HTR1A CA12 4277/4885CA1 2569/4885CA2 4215/4885
US-20250340513-A1 NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS HTR2A, HTR2C, HTR3A CA12 4068/4885CA1 2256/4885CA2 3924/4885
US-12605353-B2 PDIA4 inhibitors and use thereof for inhibiting β-cell pathogenesis and treating diabetes PDIA4, PDIA5, PDIA6 CA12 2518/4885CA1 1782/4885CA2 1213/4885
US-12344582-B2 Mixed serotonin 5-HT2A/2C receptor agonists and methods for treating pain and depression HTR2A, HTR2C, HTR3A CA12 4149/4885CA1 3784/4885CA2 2724/4885
US-20250091991-A1 MIXED SEROTONIN 5-HT2A/2C RECEPTOR AGONISTS AND METHODS FOR TREATING PAIN AND DEPRESSION HTR2A, HTR2C, HTR3A CA12 4149/4885CA1 3784/4885CA2 2724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.