Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGLEC9 | Q9Y336 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | SCD | O00767 | 8/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987185 | 0.82 | SIGLEC9 (0.45) | SIGLEC9EPHX2SCDALDH1A1RAB9A | |
| SCHEMBL6976928 | 0.80 | SCD (0.54) | SCD | |
| SCHEMBL6345789 | 0.79 | EPHX2 (0.56) | SIGLEC9EPHX2 | |
| SCHEMBL6984405 | 0.79 | SCD (0.50) | EPHX2SCD | |
| SCHEMBL31023936 | 0.78 | GPR119 (0.65) | SIGLEC9EPHX2GPR119CCNA2CDK2 | |
| SCHEMBL1876139 | 0.78 | GPR119 (0.65) | SIGLEC9EPHX2GPR119CCNA2CDK2 | |
| SCHEMBL6346302 | 0.77 | NOS2 (0.51) | SIGLEC9EPHX2SCD | |
| Hydrochloric Acid SCHEMBL6983385 | 0.76 | SIGLEC9 (0.40) | SIGLEC9EPHX2SCDMAPK1 | |
| SCHEMBL6347296 | 0.75 | SIGLEC9 (0.49) | SIGLEC9EPHX2GPR119CCNA2CDK2 | |
| SCHEMBL23022528 | 0.74 | GPR119 (0.59) | SIGLEC9EPHX2GPR119CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289950-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096296-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |