Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGLEC9 | Q9Y336 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985709 | 0.82 | SIGLEC9 (0.45) | SIGLEC9EPHX2RAB9ASCDALDH1A1 | |
| Hydrochloric Acid SCHEMBL6983385 | 0.82 | SIGLEC9 (0.40) | SIGLEC9EPHX2SCDPOLB | |
| SCHEMBL6981269 | 0.80 | SCD (0.52) | EPHX2SCD | |
| SCHEMBL6345789 | 0.77 | EPHX2 (0.56) | SIGLEC9EPHX2C3AR1 | |
| SCHEMBL6341787 | 0.76 | SIGLEC9 (0.49) | SIGLEC9EPHX2RAB9AC3AR1DRD2 | |
| SCHEMBL6346302 | 0.75 | NOS2 (0.51) | SIGLEC9EPHX2C3AR1SCDDRD2 | |
| SCHEMBL6346829 | 0.75 | SIGLEC9 (0.51) | SIGLEC9EPHX2RAB9AC3AR1DRD2 | |
| SCHEMBL111553 | 0.68 | PKM (0.58) | RAB9APOLBKMT2APKMTDP1 | |
| SCHEMBL6983386 | 0.67 | SCD (0.49) | SCD | |
| Hydrochloric Acid SCHEMBL6583478 | 0.67 | F10 (0.46) | RAB9ASCDPOLBKMT2AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289950-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096296-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |