Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672567 | 0.84 | CES1 (0.52) | KMT2AL3MBTL1TDP1MEN1CES2 | |
| SCHEMBL5680205 | 0.83 | L3MBTL1 (0.57) | KMT2AL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL6986997 | 0.81 | KMT2A (0.51) | KMT2AL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL6987142 | 0.81 | CES2 (0.52) | KMT2AL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL1515693 | 0.79 | L3MBTL1 (0.68) | KMT2AL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL28555686 | 0.79 | KMT2A (0.50) | KMT2AL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL7767316 | 0.78 | L3MBTL1 (0.66) | KMT2AL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL6546596 | 0.78 | KMT2A (0.49) | KMT2AL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL13853886 | 0.76 | KDM4E (0.54) | KMT2AL3MBTL1TDP1NPC1RAB9A | |
| 4-Methylbenzoic Acid SCHEMBL8360450 | 0.76 | ALDH1A1 (0.63) | KMT2AL3MBTL1TDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294695-A2 | SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-03-26 | — | — | EP | claimed |
| WO-2001085694-A2 | SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-11-15 | — | — | WO | claimed |