Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160276 | 0.80 | HSD11B1 (0.33) | MALT1 | |
| SCHEMBL6972533 | 0.78 | POLB (0.30) | KMT2A | |
| SCHEMBL6979923 | 0.74 | MALT1 (0.33) | MALT1 | |
| SCHEMBL7154413 | 0.66 | KDM4E (0.32) | KMT2AALDH1A1MEN1 | |
| SCHEMBL6979990 | 0.65 | MALT1 (0.32) | MALT1 | |
| SCHEMBL7158040 | 0.64 | CA12 (0.40) | KMT2AALDH1A1MAPTMEN1NPC1 | |
| SCHEMBL6982298 | 0.62 | KDM4E (0.42) | KMT2AALDH1A1MAPTESR2MEN1 | |
| SCHEMBL30521427 | 0.59 | NPC1 (0.34) | KMT2AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL5649611 | 0.58 | CES2 (0.65) | KMT2AALDH1A1ESR1ESR2MEN1 | |
| SCHEMBL2829946 | 0.58 | KMT2A (0.63) | KMT2AALDH1A1MAPTESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177194-B1 | 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS | BASF AG (DE) | 2003-09-17 | — | — | EP | disclosed |
| US-6541423-B1 | Controlling vegatation | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-01 | — | — | US | disclosed |