Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | KHK | P50053 | 6/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.35 |
| ▸ | CACNB4 | O00305 | 3/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 3/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.35 |
| ▸ | CACNG3 | O60359 | 3/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 3/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.35 |
| ▸ | CACNG7 | P62955 | 3/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.35 |
| ▸ | CACNG1 | Q06432 | 3/20 | 0.35 |
| ▸ | CACNB2 | Q08289 | 3/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983913 | 0.88 | HRH3 (0.47) | HRH3CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL7141579 | 0.85 | CACNB4 (0.47) | HRH3CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL6986812 | 0.81 | ALDH1A1 (0.40) | TSHRSMN1; SMN2 | |
| SCHEMBL6985846 | 0.80 | BCL2 (0.41) | TSHRSMN1; SMN2 | |
| SCHEMBL6982469 | 0.79 | CYP2C9 (0.39) | TSHRSMN1; SMN2 | |
| SCHEMBL6986283 | 0.79 | HTR2C (0.42) | KHK | |
| SCHEMBL6987183 | 0.78 | TSHR (0.45) | TSHRSMN1; SMN2 | |
| SCHEMBL6983758 | 0.78 | HTT (0.41) | TSHRKCNH2SMN1; SMN2 | |
| SCHEMBL6982995 | 0.77 | HRH3 (0.39) | HRH3 | |
| SCHEMBL6984642 | 0.77 | HRH3 (0.39) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |