Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2288364 | 0.85 | MAPT (0.64) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL8983504 | 0.82 | MAPT (0.69) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL6986158 | 0.81 | MAPT (0.68) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL6986153 | 0.81 | MAPT (0.68) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL23720127 | 0.80 | L3MBTL1 (0.58) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL4678382 | 0.80 | MEN1 (0.49) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL4100624 | 0.77 | ALDH1A1 (0.55) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL6728267 | 0.77 | MEN1 (0.63) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL4682287 | 0.76 | KMT2A (0.51) | MAPTALDH1A1GAATDP1MEN1 | |
| SCHEMBL10384384 | 0.76 | KMT2A (0.47) | MAPTALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0113070-B1 | THE USE OF SUBSTITUTED NITRO AND CYANOGUANIDINES FOR INCREASING CROP YIELD | AMERICAN CYANAMID COMPANY (US) | 1988-01-13 | — | — | EP | claimed |
| US-4594092-A | Cytokinin-like response | AMERICAN CYANAMID COMPANY (US) | 1986-06-10 | — | — | US | claimed |
| EP-0113070-A1 | The use of substituted nitro and cyanoguanidines for increasing crop yield | AMERICAN CYANAMID COMPANY (US) | 1984-07-11 | — | — | EP | claimed |
| EP-1392655-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2008-07-16 | — | — | EP | disclosed |
| EP-1198456-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2007-09-19 | — | — | EP | disclosed |
| EP-0507317-B1 | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives | OTSUKA PHARMA CO LTD (JP) | 1997-01-15 | — | — | EP | disclosed |
| EP-0507317-A2 | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |
| US-4944788-A | Substituted nitro and cyanoguanidines and their use for increasing crop yields | AMERICAN CYANAMID COMPANY (US) | 1990-07-31 | — | — | US | disclosed |
| US-4804780-A | PLANT GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1989-02-14 | — | — | US | disclosed |
| EP-0113070-B1 | THE USE OF SUBSTITUTED NITRO AND CYANOGUANIDINES FOR INCREASING CROP YIELD | AMERICAN CYANAMID COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |
| EP-0189579-A1 | Substituted nitro and cyanoguanidines and their use for increasing crop yield | AMERICAN CYANAMID COMPANY (US) | 1986-08-06 | — | — | EP | disclosed |
| US-4594092-A | Cytokinin-like response | AMERICAN CYANAMID COMPANY (US) | 1986-06-10 | — | — | US | disclosed |
| EP-0113070-A1 | The use of substituted nitro and cyanoguanidines for increasing crop yield | AMERICAN CYANAMID COMPANY (US) | 1984-07-11 | — | — | EP | disclosed |