Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16703630 | 0.84 | HSD17B10 (0.34) | DAOMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL16418603 | 0.79 | DAO (0.36) | DAOMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL10804992 | 0.77 | ALDH1A1 (0.38) | DAOMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL17002554 | 0.77 | MEN1 (0.48) | DAOMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL17362093 | 0.77 | ACLY (0.42) | DAOMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7909779 | 0.75 | ALDH1A1 (0.44) | DAOMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL1000301 | 0.75 | DAO (0.50) | DAOMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL4153740 | 0.75 | PKM (0.54) | DAOMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL574325 | 0.75 | TTK (0.44) | DAOMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL10801923 | 0.73 | DAO (0.34) | DAOALDH1A1HPGDLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4546191-A | Trifluoromethyl-2-pyridinone or pyridinthione compounds and process for the preparation of the same | ISHIHARA SANGYO KAISHA LTD. (JP) | 1985-10-08 | — | — | US | claimed |
| JP-60038363-A | — | — | None | — | — | JP | disclosed |
| JP-55124763-A | — | — | None | — | — | JP | disclosed |
| JP-62026270-A | — | — | None | — | — | JP | disclosed |
| JP-61186363-A | — | — | None | — | — | JP | disclosed |
| CN-102875453-A | Preparation method for pyridine medical intermediate for synthesizing anti-cancer auxiliary medicines | Shanghai titan chemical co ltd | 2013-01-16 | — | — | CN | disclosed |
| EP-1335903-A1 | 2-ARYL-5-TRIFLUOROMETHYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002042275-A1 | 2-ARYL-5-TRIFLUOROMETHYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-30 | — | — | WO | disclosed |
| WO-1994021606-A1 | PENTAFLUOROSULPHANYLPHENYL AND PENTAFLUOROSULPHANYLPYRIDIL SUBSTITUTED HETEROAROMATIC COMPOUNDS WITH INSECTICIDAL OR ACARICIDAL ACTIVITY | ZENECA LIMITED (GB) | 1994-09-29 | — | — | WO | disclosed |
| JP-S6226270-A | 5-TRIFLUOROMETHYL-2-PYRIDONE DERIVATIVE | ISHIHARA SANGYO KAISHA LTD | 1987-02-04 | — | — | JP | disclosed |
| JP-S61186363-A | PRODUCTION OF PYRIDYLPYRIDONE DERIVATIVE | SUMITOMO CHEM CO LTD | 1986-08-20 | — | — | JP | disclosed |
| US-4546191-A | Trifluoromethyl-2-pyridinone or pyridinthione compounds and process for the preparation of the same | ISHIHARA SANGYO KAISHA LTD. (JP) | 1985-10-08 | — | — | US | disclosed |
| JP-S6038363-A | PYRIDYLPYPYRIDONE DERIVATIVE AND INSECTICIDE CONTAINING IT AS ACTIVE INGREDIENT | SUMITOMO CHEM CO LTD | 1985-02-27 | — | — | JP | disclosed |
| US-4404388-A | REACTING A 1H-PYRID-2-ONE WITH PHOSGENE USING A SOLVENT AND TERITARY AMIDE | CIBA-GEIGY CORPORATION (US) | 1983-09-13 | — | — | US | disclosed |
| EP-0072777-A2 | Process for the preparation of 2-chloropyridines | CIBA-GEIGY AG (CH) | 1983-02-23 | — | — | EP | disclosed |
| JP-S55124763-A | 5-TRIFLUOROMETHYL-2-PYRIDONE DERIVATIVE | ISHIHARA SANGYO KAISHA LTD | 1980-09-26 | — | — | JP | disclosed |