Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987058 | 0.76 | SMN1; SMN2 (0.58) | ADRA1ASMN1; SMN2TAAR1 | |
| SCHEMBL6985668 | 0.75 | KMT2A (0.62) | SMN1; SMN2KMT2A | |
| SCHEMBL5002972 | 0.71 | ALDH1A1 (0.53) | SLC40A1KMT2A | |
| SCHEMBL7956237 | 0.69 | GAA (0.44) | SMN1; SMN2KMT2A | |
| SCHEMBL6071694 | 0.68 | KDM4E (0.49) | ADRA1ATAAR1 | |
| SCHEMBL6986013 | 0.67 | CYP11B1 (0.53) | — | |
| SCHEMBL1145362 | 0.67 | ALDH1A1 (0.54) | SMN1; SMN2SLC40A1KMT2A | |
| SCHEMBL6238697 | 0.66 | ALDH1A1 (0.53) | SLC40A1KMT2A | |
| SCHEMBL8224003 | 0.66 | ALDH1A1 (0.53) | SLC40A1KMT2A | |
| SCHEMBL13211030 | 0.66 | ALDH1A1 (0.58) | SLC40A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324999-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002030927-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2002-04-18 | — | — | WO | disclosed |