Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940963 | 0.88 | CTSL (0.41) | — | |
| SCHEMBL6940310 | 0.88 | MMP3 (0.44) | MMP1MMP3MMP9MMP13MMP8 | |
| SCHEMBL7853162 | 0.86 | MMP1 (0.46) | MMP1MMP3MMP9MMP13MMP8 | |
| SCHEMBL7853167 | 0.86 | MMP1 (0.46) | MMP1MMP3MMP9MMP13MMP8 | |
| SCHEMBL7836454 | 0.86 | MMP1 (0.46) | MMP1MMP3MMP9MMP13MMP8 | |
| SCHEMBL7827850 | 0.86 | MMP1 (0.46) | MMP1MMP3MMP9MMP13MMP8 | |
| SCHEMBL6943292 | 0.84 | MMP3 (0.45) | MMP1MMP3MMP9HPGDMMP8 | |
| SCHEMBL6659520 | 0.84 | MMP3 (0.45) | MMP1MMP3MMP9HPGDMMP8 | |
| SCHEMBL6659518 | 0.84 | MMP3 (0.45) | MMP1MMP3MMP9HPGDMMP8 | |
| SCHEMBL6943287 | 0.84 | MMP3 (0.45) | MMP1MMP3MMP9HPGDMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089964-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-10-29 | — | — | EP | disclosed |