Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272095 | 0.75 | NR1H2 (0.40) | LMNAESR1ESR2NR1H2NR1H3 | |
| SCHEMBL4729166 | 0.74 | ESR1 (0.32) | ESR1ESR2 | |
| SCHEMBL3481615 | 0.74 | ESR1 (0.34) | LMNAESR1ESR2NR1H2NR1H3 | |
| SCHEMBL272865 | 0.73 | ESR1 (0.37) | LMNAESR1ESR2NR1H2NR1H3 | |
| SCHEMBL3482130 | 0.73 | ESR1 (0.37) | LMNAESR1ESR2NR1H2NR1H3 | |
| SCHEMBL271913 | 0.73 | ESR1 (0.37) | LMNAESR1ESR2NR1H2NR1H3 | |
| SCHEMBL28742802 | 0.70 | CETP (0.41) | LMNA | |
| SCHEMBL272467 | 0.69 | ESR1 (0.34) | LMNAESR1ESR2NR1H2NR1H3 | |
| SCHEMBL1263705 | 0.69 | — | — | |
| SCHEMBL28496602 | 0.69 | TP53 (0.35) | ESR1ESR2NR1H2NR1H3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410238-B2 | Bishydroxyarylsiloxane compound and method of preparing the same | CHEIL INDUSTRIES INC. (KR) | 2013-04-02 | — | — | US | disclosed |
| EP-2423245-B1 | Bishydroxyarylsiloxane and preparation method thereof | CHEIL IND INC (KR) | 2013-03-06 | — | — | EP | disclosed |
| US-20120053316-A1 | Bishydroxyarylsiloxane Compound and Method of Preparing the Same | CHEIL INDUSTRIES INC. (KR) | 2012-03-01 | — | — | US | disclosed |
| EP-2423245-A1 | Bishydroxyarylsiloxane and preparation method thereof | Cheil Industries Inc. (KR) | 2012-02-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053316-A1 | Bishydroxyarylsiloxane Compound and Method of Preparing the Same | FHIT, SMCHD1, STS | LMNA 2731/4885ESR1 1944/4885ESR2 2475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.