Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12680254 | 0.83 | ESR1 (0.34) | ESR1ESR2TP53MAPT | |
| SCHEMBL11680664 | 0.83 | TP53 (0.37) | ESR1ESR2TP53MAPT | |
| SCHEMBL3481489 | 0.82 | ESR1 (0.33) | ESR1ESR2TP53MAPT | |
| SCHEMBL3482722 | 0.80 | ESR1 (0.32) | ESR1ESR2TP53MAPT | |
| SCHEMBL3481608 | 0.78 | LMNA (0.35) | ESR1ESR2TP53 | |
| SCHEMBL28834371 | 0.78 | LTA4H (0.33) | — | |
| SCHEMBL13089075 | 0.77 | ESR1 (0.31) | ESR1ESR2 | |
| SCHEMBL12401084 | 0.76 | LTA4H (0.37) | — | |
| SCHEMBL8893511 | 0.75 | — | — | |
| SCHEMBL3481678 | 0.74 | LTA4H (0.36) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008051947-A2 | HIGHLY FILLED POLYMER MATERIALS | LORD CORPORATION (US) | 2008-05-02 | — | — | WO | disclosed |
| EP-0665007-B1 | Method of making clear antiperspirant gels | DOW CORNING (US) | 1999-03-10 | — | — | EP | disclosed |
| EP-0883396-A1 | CONTAINERS AND METHODS FOR STORING AND ADMIXING MEDICAL SOLUTIONS | BAXTER INTERNATIONAL INC. (US) | 1998-12-16 | — | — | EP | disclosed |
| WO-1998010733-A1 | CONTAINERS AND METHODS FOR STORING AND ADMIXING MEDICAL SOLUTIONS | BAXTER INTERNATIONAL INC. (US) | 1998-03-19 | — | — | WO | disclosed |
| US-5492691-A | COMBINING ANTIPERSPIRANT, A CLEAR ANHYDROUS ORGANIC OIL-FREE GEL FORMED WITH 12-HYDROXYSTEARIC ACID GELATOR AND AN AROMATIC CONTAINING SILICONE FLUID OR BLEND OF SILICONE FLUIDS | DOW CORNING CORPORATION (US) | 1996-02-20 | — | — | US | disclosed |
| EP-0665256-A2 | Pristine phenylpropylalkylsiloxanes | DOW CORNING CORPORATION (US) | 1995-08-02 | — | — | EP | disclosed |
| EP-0665007-A1 | Method of making clear antiperspirant gels | DOW CORNING CORPORATION (US) | 1995-08-02 | — | — | EP | disclosed |
| US-5384383-A | Pristine phenylpropylalkylsiloxanes | DOW CORNING CORPORATION (US) | 1995-01-24 | — | — | US | disclosed |