Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2626817 | 0.80 | ADRA1D (0.63) | ADRA1AADRA1DADRA2AADRA2BADRA2C | |
| SCHEMBL2626818 | 0.72 | ADRA1D (0.61) | ADRA1AADRA1DADRA2AADRA2BADRA2C | |
| SCHEMBL4403574 | 0.72 | ADRA1D (0.61) | ADRA1AADRA1DADRA2AADRA2BADRA2C | |
| SCHEMBL4662891 | 0.71 | CA2 (0.47) | CYP11B1CYP11B2MAPTSMN1; SMN2 | |
| SCHEMBL1876579 | 0.71 | CA2 (0.50) | HRH3CYP11B1CYP11B2HRH4 | |
| SCHEMBL2626853 | 0.70 | HRH3 (0.59) | ADRA1AADRA1DADRA2AADRA2BADRA2C | |
| SCHEMBL2398615 | 0.70 | SLC6A3 (0.39) | — | |
| SCHEMBL30988956 | 0.70 | CA2 (0.50) | — | |
| SCHEMBL407413 | 0.70 | CA2 (0.50) | — | |
| SCHEMBL8349565 | 0.68 | CA2 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324999-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002030927-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2002-04-18 | — | — | WO | disclosed |