Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 4/20 | 0.33 |
| ▸ | MMP9 | P14780 | 4/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 4/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28510626 | 0.78 | — | — | |
| SCHEMBL28510625 | 0.78 | — | — | |
| SCHEMBL5474507 | 0.78 | MEN1 (0.48) | MEN1KMT2AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL1000812 | 0.78 | MEN1 (0.48) | MEN1KMT2AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL14717641 | 0.78 | MEN1 (0.48) | MEN1KMT2AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL9101145 | 0.75 | KMT2A (0.52) | MEN1KMT2AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL6950297 | 0.75 | MTNR1A (0.40) | MTNR1AMTNR1BMAOAMAOBMEN1 | |
| SCHEMBL6945466 | 0.75 | MTNR1A (0.40) | MTNR1AMTNR1BMAOAMAOBMEN1 | |
| SCHEMBL13537403 | 0.73 | MAOA (0.40) | MTNR1AMTNR1BMAOAMAOBMEN1 | |
| SCHEMBL6792263 | 0.72 | MTNR1A (0.38) | MTNR1AMTNR1BMAOAMAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318978-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | Abbott Laboratories (US) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024636-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2002-03-28 | — | — | WO | disclosed |