Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792267 | 1.00 | MTNR1A (0.38) | MTNR1AMTNR1BMAOAMAOBKMT2A | |
| SCHEMBL6790851 | 0.78 | SMN1; SMN2 (0.43) | KMT2AMEN1HTTL3MBTL1ALDH1A1 | |
| SCHEMBL6790854 | 0.78 | SMN1; SMN2 (0.43) | KMT2AMEN1HTTL3MBTL1ALDH1A1 | |
| SCHEMBL18554251 | 0.77 | MME (0.41) | ALDH1A1FFAR1 | |
| SCHEMBL13681413 | 0.74 | MTNR1A (0.44) | MTNR1AMTNR1BMAOAMAOBALDH1A1 | |
| SCHEMBL6794137 | 0.73 | LMNA (0.46) | KMT2AMEN1HTTL3MBTL1ALDH1A1 | |
| SCHEMBL2943414 | 0.73 | MTNR1A (0.47) | MTNR1AMTNR1BMAOAMAOBL3MBTL1 | |
| SCHEMBL2943420 | 0.73 | MTNR1A (0.47) | MTNR1AMTNR1BMAOAMAOBL3MBTL1 | |
| SCHEMBL6987291 | 0.72 | MTNR1A (0.42) | MTNR1AMTNR1BMAOAMAOBKMT2A | |
| SCHEMBL13503674 | 0.72 | MTNR1A (0.46) | MTNR1AMTNR1BMAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720338-B2 | BCL-X1 INHIBITING COMPOSITIONS AND METHODS OF PROMOTING APOPTOSIS IN A MAMMAL | ABBOTT LABORATORIES | 2004-04-13 | — | — | US | disclosed |