Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6987696 | 0.99 | CTDSP1 (0.56) | CTDSP1TDP1KDM4ELMNAFAAH | |
| SCHEMBL6987979 | 0.88 | KDM4E (0.59) | CTDSP1TDP1KDM4ELMNAMEN1 | |
| Hydrochloric Acid SCHEMBL6991722 | 0.87 | KDM4E (0.58) | CTDSP1TDP1KDM4ELMNAMEN1 | |
| SCHEMBL6991815 | 0.81 | ALDH1A1 (0.52) | KDM4ELMNAP2RY12MEN1KMT2A | |
| SCHEMBL6992011 | 0.80 | PKM (0.59) | KDM4EFAAHMEN1KMT2AHRH3 | |
| Hydrochloric Acid SCHEMBL6990747 | 0.80 | ALDH1A1 (0.51) | KDM4ELMNAP2RY12MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6989166 | 0.79 | PKM (0.58) | KDM4EFAAHMEN1KMT2AHRH3 | |
| Hydrochloric Acid SCHEMBL6990408 | 0.78 | KMT2A (0.51) | KDM4EFAAHMEN1KMT2AHTT | |
| SCHEMBL29313543 | 0.76 | CHRM3 (0.56) | CTDSP1TDP1KDM4ELMNAFAAH | |
| SCHEMBL6987336 | 0.75 | CNR1 (0.59) | TDP1KDM4EMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343775-A2 | PIPERAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002048124-A2 | PIPERAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-06-20 | — | — | WO | disclosed |