Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 7/20 | 0.60 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | OXTR | P30559 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988048 | 0.85 | NAAA (0.55) | AVPR1AAVPR1BNR4A2AVPR2ALDH1A1 | |
| SCHEMBL6986447 | 0.80 | AVPR1A (0.71) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL7093443 | 0.79 | ALDH1A1 (0.58) | AVPR1AAVPR1BAVPR2ALDH1A1MAPT | |
| SCHEMBL6991585 | 0.76 | AVPR1A (0.50) | AVPR1AAVPR1BAVPR2ALDH1A1MAPT | |
| SCHEMBL4146200 | 0.76 | AVPR1A (0.68) | AVPR1AAVPR1BAVPR2HPGDOXTR | |
| SCHEMBL6991806 | 0.76 | AVPR1A (0.47) | AVPR1AAVPR1BAVPR2ALDH1A1MAPT | |
| SCHEMBL6991852 | 0.76 | AVPR1A (0.49) | AVPR1AAVPR1BAVPR2ALDH1A1MAPT | |
| SCHEMBL6988528 | 0.75 | AVPR1A (1.00) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6989910 | 0.75 | AVPR1A (0.46) | AVPR1AAVPR1BAVPR2ALDH1A1MAPT | |
| SCHEMBL6202224 | 0.74 | AVPR1A (0.54) | AVPR1AAVPR1BAVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |