Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.54 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.54 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 3/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987431 | 0.85 | AVPR1A (0.60) | AVPR1AAVPR1BAVPR2NPC1RAB9A | |
| SCHEMBL4869978 | 0.85 | FAAH (0.53) | AVPR1AAVPR1BAVPR2NPC1RAB9A | |
| SCHEMBL7093443 | 0.82 | ALDH1A1 (0.58) | AVPR1AAVPR1BAVPR2HRH3NPC1 | |
| SCHEMBL4146200 | 0.81 | AVPR1A (0.68) | AVPR1AAVPR1BAVPR2HPGD | |
| SCHEMBL6991585 | 0.80 | AVPR1A (0.50) | AVPR1AAVPR1BAVPR2NPC1RAB9A | |
| SCHEMBL19454437 | 0.79 | NPC1 (0.57) | AVPR1AAVPR1BAVPR2NPC1RAB9A | |
| SCHEMBL6991954 | 0.79 | AVPR1A (0.65) | AVPR1AAVPR1BAVPR2NPC1RAB9A | |
| SCHEMBL6991852 | 0.79 | AVPR1A (0.49) | AVPR1AAVPR1BAVPR2NPC1RAB9A | |
| SCHEMBL6991806 | 0.79 | AVPR1A (0.47) | AVPR1AAVPR1BAVPR2HRH3ALDH1A1 | |
| SCHEMBL6989910 | 0.78 | AVPR1A (0.46) | AVPR1AAVPR1BAVPR2HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |