Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 9/20 | 0.49 |
| ▸ | AVPR1B | P47901 | 7/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093443 | 0.85 | ALDH1A1 (0.58) | AVPR1AAVPR1BAVPR2HPGDALDH1A1 | |
| SCHEMBL6991585 | 0.84 | AVPR1A (0.50) | AVPR1AAVPR1BAVPR2HPGDALDH1A1 | |
| SCHEMBL6988048 | 0.79 | NAAA (0.55) | AVPR1AAVPR1BAVPR2HPGDALDH1A1 | |
| SCHEMBL6990649 | 0.78 | AVPR1A (0.50) | AVPR1AAVPR1BAVPR2HPGDALDH1A1 | |
| SCHEMBL6991806 | 0.77 | AVPR1A (0.47) | AVPR1AAVPR1BAVPR2HPGDALDH1A1 | |
| SCHEMBL6989910 | 0.76 | AVPR1A (0.46) | AVPR1AAVPR1BAVPR2HPGDALDH1A1 | |
| SCHEMBL6987431 | 0.76 | AVPR1A (0.60) | AVPR1AAVPR1BAVPR2HPGDALDH1A1 | |
| SCHEMBL6985203 | 0.75 | AVPR1A (0.61) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL4146200 | 0.73 | AVPR1A (0.68) | AVPR1AAVPR1BAVPR2HPGDOXTR | |
| SCHEMBL5235720 | 0.71 | AVPR1A (0.53) | AVPR1AAVPR1BAVPR2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |