Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | FPR2 | P25090 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.36 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL696858 | 0.82 | CES2 (0.45) | NPC1RAB9ACES2TLR7SRD5A2 | |
| SCHEMBL2717104 | 0.81 | NPC1 (0.67) | NPC1RAB9AFPR2CES2CES1 | |
| SCHEMBL712135 | 0.78 | NPC1 (0.65) | NPC1RAB9ACES2CES1KDM4E | |
| SCHEMBL697784 | 0.78 | MTOR (0.47) | NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL1507800 | 0.74 | CYP19A1 (0.41) | NPC1RAB9AKDM4EALDH1A1GSK3B | |
| SCHEMBL28243558 | 0.74 | CES2 (0.58) | CES2CES1KIF11SRD5A2ALDH1A1 | |
| SCHEMBL11137294 | 0.74 | NPC1 (0.42) | NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL698757 | 0.72 | KMT2A (0.43) | NPC1RAB9ATLK2CNR2 | |
| SCHEMBL706123 | 0.71 | NPC1 (0.37) | NPC1RAB9ACES2CES1 | |
| SCHEMBL697587 | 0.71 | KMT2A (0.42) | NPC1RAB9ASRD5A2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |