Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982869 | 0.86 | PKM (0.40) | GRM5HTTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL6987183 | 0.85 | TSHR (0.45) | HTTTSHRSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL6983706 | 0.85 | HTT (0.36) | GRM5HTTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL6983515 | 0.83 | ALDH1A1 (0.38) | GRM5HTTTSHRALDH1A1 | |
| SCHEMBL6987419 | 0.83 | ALDH1A1 (0.43) | HTTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL6986812 | 0.82 | ALDH1A1 (0.40) | HTTTSHRSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL6987971 | 0.82 | HTT (0.38) | HTTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL6986605 | 0.82 | HTT (0.48) | HTTTSHRSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL6983312 | 0.81 | HTT (0.37) | HTTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL6985846 | 0.81 | BCL2 (0.41) | HTTTSHRSMN1; SMN2ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |