Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 11/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987698 | 0.86 | NPSR1 (0.45) | ACHEHTR4SIGMAR1NPSR1MEN1 | |
| SCHEMBL2481341 | 0.80 | HTR4 (0.66) | ACHEHTR4SIGMAR1TSHRMEN1 | |
| SCHEMBL6985165 | 0.79 | TSHR (0.44) | TSHRNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL8132262 | 0.76 | TAAR1 (0.51) | ACHEHTR4SIGMAR1TSHRMEN1 | |
| SCHEMBL6703732 | 0.75 | HTR4 (0.58) | ACHEHTR4SIGMAR1TSHRMEN1 | |
| SCHEMBL7688094 | 0.72 | HTR4 (0.61) | ACHEHTR4SIGMAR1TSHRMEN1 | |
| SCHEMBL6987576 | 0.72 | TSHR (0.43) | ACHEHTR4SIGMAR1TSHRMEN1 | |
| SCHEMBL6698989 | 0.70 | ACHE (0.46) | ACHEHTR4SIGMAR1TSHRMEN1 | |
| SCHEMBL11480696 | 0.67 | PTGDR2 (0.46) | MEN1KMT2AHSD17B10 | |
| SCHEMBL6984542 | 0.67 | KMT2A (0.65) | TSHRMEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |