Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592660 | 0.81 | EPHX1 (0.42) | ACHEEPHX1ALDH1A1NPC1RAB9A | |
| SCHEMBL5199197 | 0.81 | ACHE (0.44) | ACHEEPHX1ALDH1A1 | |
| SCHEMBL5199193 | 0.81 | ACHE (0.44) | ACHEEPHX1ALDH1A1 | |
| SCHEMBL2551779 | 0.75 | EPHX1 (0.50) | ACHEEPHX1ALDH1A1NPC1RAB9A | |
| SCHEMBL5553589 | 0.75 | ACHE (0.49) | ACHEEPHX1 | |
| SCHEMBL7047373 | 0.75 | EPHX1 (0.46) | ACHEEPHX1ALDH1A1NPC1RAB9A | |
| SCHEMBL17224252 | 0.74 | ACHE (0.47) | ACHEEPHX1ALDH1A1NPC1RAB9A | |
| SCHEMBL10724239 | 0.74 | EPHX1 (0.48) | ACHEEPHX1ALDH1A1NPC1RAB9A | |
| SCHEMBL14471704 | 0.74 | CTSK (0.49) | ACHEEPHX1ALDH1A1NPC1RAB9A | |
| SCHEMBL23734377 | 0.73 | ACHE (0.50) | ACHEEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090100-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-11-29 | — | — | WO | disclosed |