Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989693 | 0.81 | KMT2A (0.49) | ALDH1A1HPGDKMT2AMEN1TSHR | |
| SCHEMBL6989108 | 0.75 | NPC1 (0.45) | ALDH1A1HPGDKMT2ACYP2D6CYP2C9 | |
| SCHEMBL6989394 | 0.73 | CYP2D6 (0.43) | ALDH1A1HPGDKMT2ACYP2D6CYP2C9 | |
| SCHEMBL5200239 | 0.73 | CYP2C9 (0.66) | ALDH1A1HPGDCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1168887 | 0.70 | ALDH1A1 (0.48) | ALDH1A1HPGDKMT2ATDP1CYP2D6 | |
| SCHEMBL1168881 | 0.70 | ALDH1A1 (0.48) | ALDH1A1HPGDKMT2ATDP1CYP2D6 | |
| SCHEMBL1168884 | 0.70 | ALDH1A1 (0.48) | ALDH1A1HPGDKMT2ATDP1CYP2D6 | |
| SCHEMBL5243999 | 0.69 | SLC6A9 (0.64) | ALDH1A1HPGDKMT2ATDP1POLB | |
| SCHEMBL23052529 | 0.68 | ALDH1A1 (0.67) | ALDH1A1HPGDKMT2ACYP2D6CYP2C9 | |
| SCHEMBL7915450 | 0.68 | CYP2D6 (0.56) | ALDH1A1HPGDTDP1CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341779-A2 | HETEROCYCLIC SULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION | Wyeth (US) | 2003-09-10 | — | — | EP | claimed |
| WO-2002057252-A2 | HETEROCYCLIC SULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION | WYETH (US) | 2002-07-25 | — | — | WO | claimed |