Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.33 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.33 |
| ▸ | CPN1 | P15169 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.32 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | F2R | P25116 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4382303 | 0.91 | HPGD (0.38) | SIGMAR1HRH3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6951964 | 0.80 | LMNA (0.39) | HRH3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1501924 | 0.77 | CHEK1 (0.32) | — | |
| SCHEMBL412203 | 0.76 | CPN1 (0.36) | SLC6A2SLC6A4SLC6A3CPN1CPB2 | |
| SCHEMBL4565414 | 0.76 | CPN1 (0.36) | SLC6A2SLC6A4SLC6A3CPN1CPB2 | |
| SCHEMBL6600488 | 0.76 | SIGMAR1 (0.41) | SIGMAR1HRH3HPGDOPRD1CHRM3 | |
| SCHEMBL27511091 | 0.76 | CPN1 (0.36) | HRH3SLC6A2SLC6A4SLC6A3CPN1 | |
| SCHEMBL6989033 | 0.75 | CACNA2D1 (0.45) | SIGMAR1 | |
| SCHEMBL6965942 | 0.74 | HRH3 (0.34) | SIGMAR1HRH3HPGDOPRD1CHRM3 | |
| SCHEMBL854892 | 0.74 | DPP4 (0.37) | HRH3SLC6A2SLC6A4SLC6A3CPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289972-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096323-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |