Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKCH | P24723 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575428 | 0.90 | HSD17B10 (0.45) | LPAR1LPAR3LPAR2USP2SPHK1 | |
| SCHEMBL9575523 | 0.89 | LPAR1 (0.46) | LPAR1LPAR3LPAR2USP2SPHK1 | |
| SCHEMBL18510371 | 0.82 | LPAR1 (0.58) | LPAR1LPAR3LPAR2USP2SPHK1 | |
| SCHEMBL9575515 | 0.81 | LMNA (0.31) | — | |
| SCHEMBL6988663 | 0.80 | — | — | |
| SCHEMBL2550954 | 0.78 | LPAR1 (0.56) | LPAR1LPAR3LPAR2USP2TSHR | |
| SCHEMBL9575535 | 0.78 | HSD17B10 (0.48) | LPAR1LPAR3LPAR2USP2SPHK1 | |
| SCHEMBL9575740 | 0.78 | HSD17B10 (0.35) | LPAR1LPAR3LPAR2HSD17B10TDP1 | |
| SCHEMBL18510380 | 0.77 | PRKD3 (0.60) | LPAR1LPAR3LPAR2USP2SPHK1 | |
| SCHEMBL722046 | 0.76 | TSHR (0.42) | USP2SPHK1TSHRHTTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225550-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |
| EP-0464511-A2 | Process for the preparation of acyclic, substituted nucleosides and its intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-08 | — | — | EP | disclosed |