Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9039345 | 0.86 | ALOX5 (0.42) | ALOX5SMN1; SMN2 | |
| SCHEMBL9041380 | 0.85 | TP53 (0.42) | ALOX5PKMSMN1; SMN2 | |
| SCHEMBL6993125 | 0.83 | TSHR (0.50) | PKM | |
| SCHEMBL9039541 | 0.83 | ALOX5 (0.43) | ALOX5PKMLTA4HSMN1; SMN2 | |
| SCHEMBL6990085 | 0.80 | SMN1; SMN2 (0.43) | ALOX5LTA4HSMN1; SMN2 | |
| SCHEMBL2224578 | 0.78 | SMN1; SMN2 (0.54) | ALOX5LTA4HSMN1; SMN2TRPM8 | |
| SCHEMBL20347975 | 0.78 | REN (0.58) | ALOX5LTA4HSMN1; SMN2TRPM8 | |
| SCHEMBL9039948 | 0.77 | SMN1; SMN2 (0.40) | ALOX5SMN1; SMN2 | |
| SCHEMBL2226376 | 0.76 | SMN1; SMN2 (0.51) | ALOX5LTA4HSMN1; SMN2 | |
| SCHEMBL7203749 | 0.75 | TSHR (0.45) | PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551527-B1 | PYRROLOAZEPINE DERIVATIVE | SUNTORY LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| EP-0441349-B1 | Pyrroloazepine derivatives | SUNTORY LTD (JP) | 1996-01-03 | — | — | EP | disclosed |
| US-5416082-A | Antiserotonine agents | SUNTORY LIMITED (JP) | 1995-05-16 | — | — | US | disclosed |
| US-5397780-A | Antiserotonine, hypotensive, congestive heart failure | SUNTORY LIMITED (JP) | 1995-03-14 | — | — | US | disclosed |
| US-5391731-A | Useful therapeutics for circulatory diseases | SUNTORY LIMITED (JP) | 1995-02-21 | — | — | US | disclosed |
| EP-0551527-A1 | PYRROLOAZEPINE DERIVATIVE | SUNTORY LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5206239-A | Cardiovascular disorders | SUNTORY LIMITED (JP) | 1993-04-27 | — | — | US | disclosed |
| EP-0441349-A1 | Pyrroloazepine derivatives | SUNTORY LIMITED (JP) | 1991-08-14 | — | — | EP | disclosed |