Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 10/20 | 0.47 |
| ▸ | AVPR1B | P47901 | 8/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 8/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991988 | 0.87 | AVPR1A (0.56) | LMNATP53AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6985550 | 0.84 | AVPR2 (0.47) | AVPR1AAVPR1BAVPR2KMT2A | |
| SCHEMBL6989537 | 0.84 | AVPR1A (0.55) | AVPR1AAVPR1BAVPR2KMT2A | |
| SCHEMBL6995228 | 0.82 | AVPR2 (0.51) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6987523 | 0.82 | AVPR2 (0.56) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6988903 | 0.78 | AVPR2 (0.55) | LMNATP53AVPR1AAVPR1BAVPR2 | |
| SCHEMBL7341170 | 0.74 | PYGL (0.58) | LMNAGRM5MEN1KMT2A | |
| SCHEMBL6990759 | 0.73 | AVPR1A (0.68) | AVPR1AAVPR1BAVPR2MEN1KMT2A | |
| SCHEMBL5321445 | 0.72 | AVPR1A (0.75) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6989072 | 0.72 | AVPR1A (0.55) | LMNATP53AVPR1AAVPR1BAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |