Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 10/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.51 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987523 | 0.94 | AVPR2 (0.56) | AVPR2AVPR1AAVPR1BNPC1RAB9A | |
| SCHEMBL6991988 | 0.90 | AVPR1A (0.56) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6994183 | 0.87 | AVPR2 (0.60) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6985550 | 0.87 | AVPR2 (0.47) | AVPR2AVPR1AAVPR1BMAP3K7 | |
| SCHEMBL6989537 | 0.86 | AVPR1A (0.55) | AVPR2AVPR1AAVPR1BNPC1RAB9A | |
| SCHEMBL6996850 | 0.82 | LMNA (0.51) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6989178 | 0.81 | AVPR2 (0.69) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6988903 | 0.77 | AVPR2 (0.55) | AVPR2AVPR1AAVPR1BHDAC1HDAC6 | |
| SCHEMBL6990759 | 0.75 | AVPR1A (0.68) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL5321445 | 0.75 | AVPR1A (0.75) | AVPR2AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |