Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.57 |
| ▸ | CTSS | P25774 | 4/20 | 0.57 |
| ▸ | CTSB | P07858 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26047978 | 0.90 | TRPM8 (0.58) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL418783 | 0.90 | TRPM8 (0.58) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL16270356 | 0.90 | MEN1 (0.57) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL7411035 | 0.89 | CTSL (0.55) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL24734375 | 0.89 | CTSL (0.71) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL8837344 | 0.89 | CTSL (0.71) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL221434 | 0.89 | CTSL (0.71) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL221435 | 0.89 | CTSL (0.71) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL8837339 | 0.89 | CTSL (0.71) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL5145628 | 0.89 | CTSL (0.71) | CTSLCTSSCTSBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345931-A2 | CYSTEINE PROTEASE INHIBITORS | Medivir UK Ltd (GB) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002040462-A2 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR UK LIMITED (GB) | 2002-05-23 | — | — | WO | disclosed |