Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 10/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2569037 | 0.85 | ALDH1A1 (0.44) | ADORA1ADORA2AL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL19942595 | 0.83 | ADORA1 (0.45) | ADORA1ADORA2AL3MBTL1MAPK1KDM4E | |
| SCHEMBL9069187 | 0.83 | ADORA2A (0.45) | ADORA1ADORA2AL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL27949446 | 0.81 | ADORA1 (0.43) | ADORA1ADORA2AL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL19908987 | 0.81 | SQOR (0.43) | ADORA1ADORA2AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL19737771 | 0.81 | PTGS2 (0.42) | ADORA1ADORA2AALDH1A1KDM4EADORA2B | |
| SCHEMBL22760879 | 0.81 | ADRA2C (0.47) | ADORA1ADORA2AADORA2B | |
| SCHEMBL27991888 | 0.81 | NPC1 (0.44) | ADORA1ADORA2AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL22563435 | 0.81 | ADORA1 (0.50) | ADORA1ADORA2AL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL22512473 | 0.80 | ADORA2A (0.47) | ADORA1ADORA2AL3MBTL1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339695-A1 | FARNESYLTRANSFERASE INHIBITORS | Abbott Laboratories (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002074747-A1 | FARNESYLTRANSFERASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-09-26 | — | — | WO | disclosed |