Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 5/20 | 0.48 |
| ▸ | KDM5A | P29375 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | KDM5C | P41229 | 3/20 | 0.48 |
| ▸ | KDM6B | O15054 | 2/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.48 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4A | O75164 | 2/20 | 0.48 |
| ▸ | TET3 | O43151 | 1/20 | 0.48 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ASPH | Q12797 | 1/20 | 0.48 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.48 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.48 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.48 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.48 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.48 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989809 | 0.92 | NPC1 (0.39) | KDM4CKDM5BKDM5AKDM4EKDM5C | |
| SCHEMBL19632157 | 0.77 | KDM4C (0.57) | KDM4CKDM5BKDM5AKDM4EKDM5C | |
| SCHEMBL6990109 | 0.76 | LPAR1 (0.53) | KDM4CKDM5BKDM5AKDM4EKDM5C | |
| SCHEMBL6989789 | 0.74 | KDM4C (0.53) | KDM4CKDM5BKDM5AKDM4EKDM5C | |
| SCHEMBL19615732 | 0.73 | KDM4E (0.51) | KDM4CKDM5BKDM5AKDM4EKDM5C | |
| SCHEMBL19631979 | 0.73 | KDM4E (0.51) | KDM4CKDM5BKDM5AKDM4EKDM5C | |
| SCHEMBL17819893 | 0.72 | FTO (0.67) | KDM4CKDM5BKDM5AKDM4EKDM5C | |
| SCHEMBL6988711 | 0.71 | CA12 (0.51) | KDM4CKDM5BKDM5AKDM4EKDM5C | |
| SCHEMBL19615734 | 0.70 | KDM4C (0.48) | KDM4CKDM5BKDM5AKDM4EKDM5C | |
| SCHEMBL29723246 | 0.70 | KDM4C (0.67) | KDM4CKDM5BKDM5AKDM4EKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |