Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | TPMT | P51580 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALKBH5 | Q6P6C2 | 3/20 | 0.49 |
| ▸ | KDM6B | O15054 | 2/20 | 0.49 |
| ▸ | KDM5C | P41229 | 2/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.49 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TET3 | O43151 | 1/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988718 | 0.92 | RAB9A (0.41) | CA12CA1CA2CA4CA6 | |
| SCHEMBL6993029 | 0.77 | ALDH1A1 (0.48) | CA12CA1CA2CA4CA6 | |
| SCHEMBL6986935 | 0.77 | KDM5A (0.49) | FTOKDM4CKDM4EALKBH5KDM6B | |
| SCHEMBL2932540 | 0.75 | CYP1A1 (0.48) | CA12CA1CA2CA4CA6 | |
| SCHEMBL2931194 | 0.73 | PDE4A (0.56) | — | |
| SCHEMBL17819893 | 0.73 | FTO (0.67) | FTOKDM4CKDM4EALKBH5KDM6B | |
| SCHEMBL6071187 | 0.73 | PDE4B (0.46) | — | |
| SCHEMBL15129879 | 0.71 | KDM4C (0.61) | CA12CA1CA2CA4CA6 | |
| SCHEMBL6989808 | 0.71 | KDM4C (0.48) | CA1CA2FTOKDM4CKDM4E | |
| Veratric Acid SCHEMBL976032 | 0.70 | CA12 (1.00) | CA12CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |