Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.53 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.48 |
| ▸ | KDM5A | P29375 | 3/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | TET3 | O43151 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 1/20 | 0.46 |
| ▸ | ASPH | Q12797 | 1/20 | 0.46 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.46 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.46 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.46 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.46 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.46 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990114 | 0.93 | LPAR1 (0.49) | LPAR1LPAR5ALDH1A1SMN1; SMN2ALOX5 | |
| SCHEMBL6986947 | 0.87 | LPAR1 (0.51) | LPAR1LPAR5KDM4CKDM5AKDM5B | |
| SCHEMBL6239722 | 0.86 | KDM5B (0.49) | LPAR1LPAR5KDM4CKDM5AKDM5B | |
| SCHEMBL6985928 | 0.86 | KDM5B (0.49) | KDM4CKDM5AKDM5BALDH1A1KDM4E | |
| SCHEMBL6993029 | 0.86 | ALDH1A1 (0.48) | KDM4CKDM5AKDM5BALDH1A1KDM4E | |
| SCHEMBL6235516 | 0.84 | KDM4C (0.49) | LPAR1LPAR5KDM4CKDM5AKDM5B | |
| SCHEMBL6990533 | 0.80 | SLC2A1 (0.53) | LPAR1LPAR5ALDH1A1MAPTMEN1 | |
| SCHEMBL6986949 | 0.80 | SLC2A1 (0.48) | LPAR1LPAR5POLBNR3C2SLC2A1 | |
| SCHEMBL18864232 | 0.80 | FTO (0.53) | KDM4CKDM5AKDM5BALDH1A1KDM4E | |
| SCHEMBL6989313 | 0.80 | SMN1; SMN2 (0.47) | LPAR1LPAR5KDM4CKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |