Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974020 | 0.86 | ALDH1A1 (0.32) | ALDH1A1HPGDTP53MAPK1NPC1 | |
| SCHEMBL7973903 | 0.84 | ALDH1A1 (0.36) | ALDH1A1HPGDTP53MAPK1NPC1 | |
| Hydrochloric Acid SCHEMBL6990489 | 0.74 | TBXAS1 (0.46) | TBXAS1ALDH1A1HPGDTP53MAPK1 | |
| SCHEMBL9871883 | 0.68 | TBXAS1 (0.51) | TBXAS1ALDH1A1NPC1RAB9APDK1 | |
| SCHEMBL31563842 | 0.65 | EPHX2 (0.44) | ALDH1A1HPGDMAPK1BTKNPC1 | |
| SCHEMBL31564285 | 0.65 | EPHX2 (0.41) | BTKKMT2AL3MBTL1 | |
| SCHEMBL31563886 | 0.64 | ALDH1A1 (0.43) | TBXAS1ALDH1A1HPGDTP53MAPK1 | |
| Hydrochloric Acid SCHEMBL6998122 | 0.64 | PDK1 (0.47) | ALDH1A1HPGDMAPK1NPC1POLB | |
| SCHEMBL1397675 | 0.64 | ALDH1A1 (0.53) | ALDH1A1HPGDTP53MAPK1NPC1 | |
| Hydrochloric Acid SCHEMBL6998111 | 0.64 | PDK1 (0.46) | ALDH1A1HPGDMAPK1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927177-B1 | NOVEL BENZOTHIOPHENE DERIVATIVES, THEIR PREPARATION AND USE AS UROKINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-11-26 | — | — | EP | disclosed |
| US-6274619-B1 | FUSED AMIDINO TYPE COMPOUNDS SUCH AS 4-(N-BUTYLCARBAMOYLMETHYLIDENE)-2-AMIDINO-4,5,6,7-TETRAHYDROBE NZO(B)THIOPHENE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-14 | — | — | US | disclosed |