Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
| ▸ | GABRE | P78334 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837204 | 0.84 | TBXAS1 (0.38) | TBXAS1PDK1CYP1A2ALDH1A1NPC1 | |
| SCHEMBL6987113 | 0.80 | PDK1 (0.49) | TBXAS1PDK1ALDH1A1P2RX3 | |
| Hydrochloric Acid SCHEMBL6990489 | 0.72 | TBXAS1 (0.46) | TBXAS1PDK1CYP1A2DAOALDH1A1 | |
| SCHEMBL21962476 | 0.69 | DRD2 (0.43) | TBXAS1PDK1CYP1A2 | |
| SCHEMBL9837142 | 0.68 | TBXAS1 (1.00) | TBXAS1ALDH1A1 | |
| SCHEMBL10674301 | 0.68 | FAAH (0.38) | CYP1A2ALDH1A1 | |
| SCHEMBL3555590 | 0.68 | DAO (0.48) | CYP1A2DAOALDH1A1NPC1RAB9A | |
| SCHEMBL15898219 | 0.68 | ALDH1A1 (0.48) | CYP1A2DAOALDH1A1NPC1RAB9A | |
| SCHEMBL6989880 | 0.68 | TBXAS1 (0.39) | TBXAS1PDK1ALDH1A1NPC1RAB9A | |
| SCHEMBL9834147 | 0.66 | TBXAS1 (0.33) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |