Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942832 | 1.00 | ALDH1A1 (0.67) | ALDH1A1MAPTKMT2AHTTNPSR1 | |
| SCHEMBL11757990 | 0.94 | MAPT (0.60) | ALDH1A1MAPTKMT2AHTTNPSR1 | |
| SCHEMBL11757978 | 0.94 | MAPT (0.60) | ALDH1A1MAPTKMT2AHTTNPSR1 | |
| SCHEMBL6989989 | 0.91 | TNFRSF1A (0.72) | ALDH1A1MAPTKMT2AHTTNPSR1 | |
| SCHEMBL6989990 | 0.91 | TNFRSF1A (0.72) | ALDH1A1MAPTKMT2AHTTNPSR1 | |
| Maleic Acid SCHEMBL28020629 | 0.84 | BCL2L1 (0.68) | ALDH1A1MAPTKMT2ALMNATNFRSF1A | |
| Fumaric Acid SCHEMBL4344816 | 0.81 | PARP10 (0.50) | ALDH1A1MAPTKMT2ALMNATNFRSF1A | |
| SCHEMBL28024599 | 0.80 | TNFRSF1A (0.64) | MAPTKMT2ALMNAHPGDTNFRSF1A | |
| SCHEMBL6451968 | 0.80 | TNFRSF1A (0.64) | MAPTKMT2ALMNAHPGDTNFRSF1A | |
| SCHEMBL10917423 | 0.80 | MAPT (1.00) | ALDH1A1MAPTKMT2AHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483868-A | ANTIULCER AGENTS ANTISECRETORY AGENTS | ROUSSEL UCLAF (FR) | 1984-11-20 | — | — | US | claimed |
| US-12139459-B2 | Enhancer of fertilization function of sperm | TOHOKU UNIVERSITY (JP) | 2024-11-12 | — | — | US | disclosed |
| CN-118684651-A | Compound capable of regulating and controlling fibroblast growth factor receptor 2 protein level and preparation method and application thereof | 四川大学 | 2024-09-24 | — | — | CN | disclosed |
| US-20220106270-A1 | ENHANCER OF FERTILIZATION FUNCTION OF SPERM | KAKE EDUCATIONAL INSTITUTION (JP) | 2022-04-07 | — | — | US | disclosed |
| US-11147796-B2 | Agent for preventing or ameliorating hearing impairment | TOHOKU UNIVERSITY (JP) | 2021-10-19 | — | — | US | disclosed |
| US-11147796-B2 | Agent for preventing or ameliorating hearing impairment | TOHOKU UNIVERSITY (JP) | 2021-10-19 | — | — | US | disclosed |
| US-10869858-B2 | Therapeutic agent for amyotrophic disorders | TOHOKU UNIVERSITY (JP) | 2020-12-22 | — | — | US | disclosed |
| US-10463647-B2 | Erythropoietin expression promoter | TOHOKU UNIVERSITY (JP) | 2019-11-05 | — | — | US | disclosed |
| US-10463647-B2 | Erythropoietin expression promoter | TOHOKU UNIVERSITY (JP) | 2019-11-05 | — | — | US | disclosed |
| US-20190224165-A1 | Agent for Preventing or Ameliorating Hearing Impairment | TOHOKU UNIVERSITY (JP) | 2019-07-25 | — | — | US | disclosed |
| WO-2014080640-A1 | ERYTHROPOIETIN EXPRESSION PROMOTER | 国立大学法人東北大学 (JP) | 2014-05-30 | — | — | WO | disclosed |
| EP-0902011-B1 | GAMMA-OXO-HOMOPHENYLALANINE DERIVATIVES AND PROCESS FOR PRODUCING HOMOPHENYLALANINE DERIVATIVES BY REDUCING THE SAME | KANEKA CORP (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-5981794-A | REACTING A BETA-BENZOYLACRYLIC ACID DERIVATIVE WITH A 1-ARYLETHYLAMINE DERIVATIVE | KANEKA CORPORATION (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0902011-A1 | $g(g)-OXO-HOMOPHENYLALANINE DERIVATIVES AND PROCESS FOR PRODUCING HOMOPHENYLALANINE DERIVATIVES BY REDUCING THE SAME | Kaneka Corporation (JP) | 1999-03-17 | — | — | EP | disclosed |
| EP-0138349-B1 | 3-BENZOYL-2-MERCAPTOPROPIONIC ACID DERIVATIES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1986-11-12 | — | — | EP | disclosed |
| US-4594197-A | 3-benzoyl-2-mercaptopropionic acid derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| EP-0138349-A1 | 3-Benzoyl-2-mercaptopropionic acid derivaties | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1985-04-24 | — | — | EP | disclosed |
| US-4483868-A | ANTIULCER AGENTS ANTISECRETORY AGENTS | ROUSSEL UCLAF (FR) | 1984-11-20 | — | — | US | disclosed |
| US-4221804-A | Mercaptoacyldihydropyrazole carboxylic acid derivatives | ROVNYAK GEORGE C | 1980-09-09 | — | — | US | disclosed |
| US-4211786-A | Mercaptoacyldihydropyrazole carboxylic acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1980-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12139459-B2 | Enhancer of fertilization function of sperm | CATSPER1, NASP, ZP1 | ALDH1A1 2062/4885MAPT 4861/4885KMT2A 3412/4885 |
| US-11147796-B2 | Agent for preventing or ameliorating hearing impairment | SLC26A4, OTC, SLC25A20 | ALDH1A1 477/4885MAPT 4510/4885KMT2A 4378/4885 |
| US-20220106270-A1 | ENHANCER OF FERTILIZATION FUNCTION OF SPERM | CATSPER1, NASP, ZP1 | ALDH1A1 2062/4885MAPT 4861/4885KMT2A 3412/4885 |
| US-20190224165-A1 | Agent for Preventing or Ameliorating Hearing Impairment | SLC26A4, OTC, SLC25A20 | ALDH1A1 477/4885MAPT 4510/4885KMT2A 4378/4885 |
| US-10869858-B2 | Therapeutic agent for amyotrophic disorders | SMN1; SMN2, MYOF, MUSK | ALDH1A1 1373/4885MAPT 747/4885KMT2A 3952/4885 |
| US-10463647-B2 | Erythropoietin expression promoter | EPOR, NFE2L2, FOXO1 | ALDH1A1 630/4885MAPT 4882/4885KMT2A 3254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.