Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9798236 | 1.00 | TNFRSF1A (0.62) | TNFRSF1ACYP1A2CYP2C19SMN1; SMN2LMNA | |
| SCHEMBL6989990 | 0.86 | TNFRSF1A (0.72) | TNFRSF1ACYP1A2CYP2C19SMN1; SMN2LMNA | |
| SCHEMBL6989989 | 0.86 | TNFRSF1A (0.72) | TNFRSF1ACYP1A2CYP2C19SMN1; SMN2LMNA | |
| SCHEMBL6451968 | 0.80 | TNFRSF1A (0.64) | TNFRSF1ACYP1A2CYP2C19SMN1; SMN2LMNA | |
| SCHEMBL28024599 | 0.80 | TNFRSF1A (0.64) | TNFRSF1ACYP1A2CYP2C19SMN1; SMN2LMNA | |
| SCHEMBL18480636 | 0.80 | MAPT (0.60) | CYP1A2CYP2C19LMNAHPGDALOX12 | |
| SCHEMBL11877271 | 0.78 | ALDH1A1 (0.75) | SMN1; SMN2LMNAHPGDALOX12ATM | |
| SCHEMBL4738896 | 0.78 | RAB9A (0.58) | SMN1; SMN2LMNAALOX12MAOAMAOB | |
| SCHEMBL9605450 | 0.78 | RAB9A (0.58) | SMN1; SMN2LMNAALOX12MAOAMAOB | |
| SCHEMBL11877275 | 0.78 | ALDH1A1 (0.75) | SMN1; SMN2LMNAHPGDALOX12ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240320-B1 | PHENYLPYRIDINE DERIVATIVES | Chisso Corporation (JP) | 1991-02-27 | — | — | EP | disclosed |
| US-4772416-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1988-09-20 | — | — | US | disclosed |
| EP-0240320-A2 | Phenylpyridine derivatives | Chisso Corporation (JP) | 1987-10-07 | — | — | EP | disclosed |