Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 7/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | PRKX | P51817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6996652 | 1.00 | ROCK2 (0.42) | ROCK2ROCK1KDM4CRPS6KA5MAP4K4 | |
| SCHEMBL6991461 | 0.80 | ALOX15 (0.55) | ROCK2ROCK1KDM4CRPS6KA5MAP4K4 | |
| SCHEMBL6999605 | 0.80 | ALOX15 (0.55) | ROCK2ROCK1KDM4CRPS6KA5MAP4K4 | |
| SCHEMBL7000497 | 0.77 | ROCK2 (0.43) | ROCK2ROCK1KDM4CRPS6KA5MAP4K4 | |
| SCHEMBL6994625 | 0.72 | POLB (0.53) | ROCK2ROCK1ALDH1A1KMT2A | |
| SCHEMBL20318831 | 0.70 | KDM4E (0.52) | CDK2ALDH1A1NAMPTRAB9ATSHR | |
| SCHEMBL21460379 | 0.70 | KDM4E (0.52) | CDK2ALDH1A1NAMPTRAB9ATSHR | |
| SCHEMBL26049725 | 0.69 | LTA4H (0.43) | ROCK2ROCK1MAP4K4PRKACAFLT1 | |
| SCHEMBL9046891 | 0.68 | ALDH1A1 (0.54) | ALDH1A1KMT2A | |
| SCHEMBL8134776 | 0.68 | ALDH1A1 (0.54) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037633-B1 | ANTIVIRAL COMPOUNDS | IAF BIOCHEM INT (CA) | 2003-09-10 | — | — | EP | claimed |