Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29173883 | 0.74 | NPC1 (0.33) | RAB9ANPC1KMT2AHPGDTSHR | |
| SCHEMBL11518067 | 0.72 | RAB9A (0.45) | RAB9ANPC1KMT2AHPGDTSHR | |
| SCHEMBL11517362 | 0.70 | KMT2A (0.43) | RAB9ANPC1KMT2AHPGDTSHR | |
| SCHEMBL966816 | 0.69 | MEN1 (0.58) | KMT2AIDO1MEN1PKMCTDSP1 | |
| SCHEMBL2951287 | 0.69 | NPC1 (0.53) | RAB9ANPC1KMT2AHPGDTSHR | |
| SCHEMBL1848023 | 0.68 | ALDH1A1 (0.42) | HPGDTSHRPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL28045359 | 0.68 | CYP1A2 (0.42) | HPGDTSHRIDO1PKMCTDSP1 | |
| SCHEMBL7428096 | 0.67 | MEN1 (0.55) | KMT2AIDO1MEN1PKMCTDSP1 | |
| SCHEMBL2944706 | 0.66 | MAOA (0.50) | RAB9ANPC1KMT2AHPGDTSHR | |
| SCHEMBL11277736 | 0.65 | IDO1 (0.57) | KMT2AIDO1MEN1PKMCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318978-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | Abbott Laboratories (US) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024636-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2002-03-28 | — | — | WO | disclosed |