Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744778 | 0.92 | TAS1R3 (0.46) | TAS1R3TAS1R1LPAR1LMNASMN1; SMN2 | |
| SCHEMBL6997712 | 0.91 | LPAR1 (0.40) | TAS1R3TAS1R1LPAR1LMNASMN1; SMN2 | |
| SCHEMBL6992821 | 0.84 | TAS1R3 (0.45) | TAS1R3TAS1R1LPAR1LMNASMN1; SMN2 | |
| Bicarbonate SCHEMBL9117401 | 0.82 | NPC1 (0.41) | TAS1R3TAS1R1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL7960936 | 0.81 | LMNA (0.40) | LPAR1LMNASMN1; SMN2L3MBTL1ANO1 | |
| SCHEMBL7957892 | 0.79 | LMNA (0.36) | LPAR1LMNASMN1; SMN2L3MBTL1RXFP1 | |
| SCHEMBL6994763 | 0.79 | LMNA (0.37) | LPAR1LMNASMN1; SMN2L3MBTL1RXFP1 | |
| SCHEMBL8862522 | 0.79 | TAS1R3 (0.49) | TAS1R3TAS1R1LPAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4433288 | 0.78 | TAS1R3 (0.42) | TAS1R3TAS1R1LPAR1LMNASMN1; SMN2 | |
| SCHEMBL13527323 | 0.77 | TAS1R3 (0.35) | TAS1R3TAS1R1LPAR1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754175-B1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-01-29 | — | — | EP | disclosed |
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |
| WO-1995026954-A1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-12 | — | — | WO | disclosed |