Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990974 | 0.92 | TAS1R3 (0.43) | TAS1R3TAS1R1HTTALDH1A1LMNA | |
| SCHEMBL6992821 | 0.90 | TAS1R3 (0.45) | TAS1R3TAS1R1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL8862522 | 0.84 | TAS1R3 (0.49) | TAS1R3TAS1R1ALDH1A1SMN1; SMN2LPAR1 | |
| SCHEMBL13527323 | 0.82 | TAS1R3 (0.35) | TAS1R3TAS1R1HTTLMNAL3MBTL1 | |
| SCHEMBL6997712 | 0.82 | LPAR1 (0.40) | TAS1R3TAS1R1HTTALDH1A1LMNA | |
| SCHEMBL6994975 | 0.80 | LMNA (0.36) | TAS1R3TAS1R1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL8874342 | 0.78 | HPGD (0.38) | HTTLMNAL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL8556633 | 0.77 | TAS1R3 (0.47) | TAS1R3TAS1R1HTTALDH1A1LMNA | |
| SCHEMBL6998326 | 0.77 | TAS1R3 (0.47) | TAS1R3TAS1R1ALDH1A1MEN1KMT2A | |
| SCHEMBL8558779 | 0.77 | TAS1R3 (0.47) | TAS1R3TAS1R1HTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456063-B1 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5258527-A | Insecticidal, acaricidal and herbicidal 1-H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-02 | — | — | US | disclosed |
| EP-0456063-A2 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1991-11-13 | — | — | EP | disclosed |