Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9593911 | 0.90 | HPGD (0.36) | LMNASMN1; SMN2L3MBTL1KMT2ACNR2 | |
| SCHEMBL7959947 | 0.90 | SMN1; SMN2 (0.36) | LMNASMN1; SMN2L3MBTL1LPAR1KMT2A | |
| SCHEMBL7960936 | 0.84 | LMNA (0.40) | LMNASMN1; SMN2L3MBTL1LPAR1KMT2A | |
| SCHEMBL7959906 | 0.82 | KMT2A (0.39) | LMNASMN1; SMN2L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL6994763 | 0.81 | LMNA (0.37) | LMNASMN1; SMN2L3MBTL1LPAR1KMT2A | |
| SCHEMBL6990974 | 0.79 | TAS1R3 (0.43) | LMNASMN1; SMN2L3MBTL1LPAR1KMT2A | |
| SCHEMBL7960037 | 0.78 | SMN1; SMN2 (0.40) | LMNASMN1; SMN2L3MBTL1LPAR1KMT2A | |
| SCHEMBL7958365 | 0.76 | SMN1; SMN2 (0.37) | LMNASMN1; SMN2L3MBTL1LPAR1KMT2A | |
| SCHEMBL8863114 | 0.76 | P2RX7 (0.41) | SMN1; SMN2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL6921814 | 0.75 | ALDH1A1 (0.45) | SMN1; SMN2L3MBTL1KMT2APKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |