Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10590777 | 0.81 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CYP3A4ALOX15TSHR | |
| SCHEMBL132688 | 0.80 | TDP1 (0.52) | ALDH1A1L3MBTL1CYP3A4ALOX15TSHR | |
| SCHEMBL13362748 | 0.78 | SMN1; SMN2 (0.44) | ALDH1A1L3MBTL1CYP3A4ALOX15TSHR | |
| SCHEMBL2679196 | 0.78 | ALDH1A1 (0.78) | ALDH1A1L3MBTL1CYP3A4ALOX15TSHR | |
| SCHEMBL20746963 | 0.77 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CYP3A4ALOX15TSHR | |
| SCHEMBL15325739 | 0.76 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1CYP3A4ALOX15TSHR | |
| SCHEMBL21141303 | 0.75 | RAB9A (0.70) | SMN1; SMN2RAB9ALMNACA12KMT2A | |
| SCHEMBL1820670 | 0.73 | RAB9A (0.47) | ALDH1A1L3MBTL1CYP3A4ALOX15TSHR | |
| SCHEMBL12096331 | 0.73 | RAB9A (0.47) | ALDH1A1L3MBTL1CYP3A4ALOX15TSHR | |
| SCHEMBL22773555 | 0.73 | RAB9A (0.44) | ALDH1A1L3MBTL1CYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349833-A1 | INDOLE AND DIHYDROINDOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002044149-A1 | INDOLE AND DIHYDROINDOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-06-06 | — | — | WO | disclosed |