Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992829 | 0.86 | MAPT (0.46) | MAPTL3MBTL1ALDH1A1CFTRKDM4E | |
| SCHEMBL6991899 | 0.86 | MAPT (0.51) | MAPTL3MBTL1ALDH1A1CFTRKDM4E | |
| SCHEMBL6238400 | 0.85 | SLC2A1 (0.46) | MAPTL3MBTL1ALDH1A1CFTRKDM4E | |
| SCHEMBL5210605 | 0.85 | CFTR (0.55) | MAPTL3MBTL1ALDH1A1CFTRKDM4E | |
| SCHEMBL6990533 | 0.82 | SLC2A1 (0.53) | MAPTALDH1A1KMT2AMEN1SLC2A1 | |
| SCHEMBL5210601 | 0.78 | KDM4E (0.56) | MAPTL3MBTL1ALDH1A1CFTRKDM4E | |
| SCHEMBL6987913 | 0.78 | KDM4E (0.48) | L3MBTL1ALDH1A1CFTRKDM4EKMT2A | |
| SCHEMBL5215161 | 0.78 | USP2 (0.53) | MAPTL3MBTL1ALDH1A1CYP3A4KDM4E | |
| SCHEMBL5214358 | 0.78 | PPARG (0.55) | MAPTL3MBTL1ALDH1A1CFTRKMT2A | |
| SCHEMBL6238397 | 0.77 | ALDH1A1 (0.54) | MAPTL3MBTL1ALDH1A1CFTRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |