Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987911 | 0.92 | ALDH1A1 (0.49) | KDM4EHSD17B10LMNARECQLPOLB | |
| SCHEMBL5210605 | 0.86 | CFTR (0.55) | KDM4EKMT2ACFTRTSHRL3MBTL1 | |
| SCHEMBL6238400 | 0.83 | SLC2A1 (0.46) | KDM4ELMNAPOLBKMT2ACFTR | |
| SCHEMBL6985142 | 0.80 | PKM (0.46) | PKMKMT2ACFTRNPSR1HPGD | |
| SCHEMBL6236957 | 0.80 | MAPT (0.51) | KMT2ACFTRHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL5210601 | 0.79 | KDM4E (0.56) | KDM4EKMT2ACFTRTSHRL3MBTL1 | |
| SCHEMBL5214358 | 0.78 | PPARG (0.55) | LMNAKMT2ACFTRNPSR1TSHR | |
| SCHEMBL17250907 | 0.78 | KDM4E (0.50) | KDM4EHSD17B10LMNARECQLPOLB | |
| SCHEMBL29398881 | 0.78 | KDM4E (0.50) | KDM4EHSD17B10LMNARECQLPOLB | |
| SCHEMBL6991932 | 0.78 | MAPT (0.41) | KDM4EKMT2ACFTRL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |